Trazodone (Desyrel) is an antidepressant of the serotonin antagonist and reuptake inhibitor (SARI) class. It is a phenylpiperazine compound. Trazodone also has antianxiety (anxiolytic) and sleep-inducing (hypnotic) effects.

Trazodone is an antidepressant drug that is prescribed to treat the symptoms of depression. Besides treating depression, doctors may also prescribe trazodone to treat anxiety, schizophrenia, or uncontrolled movements that occur as a side effect of other medications.